Enantioselective Synthesis of Indole-Fused Dihydropyranones via Catalytic Cycloaddition of Ketenes and 3-Alkylenyloxindoles

被引：103

作者：

Lv, Hui ^{[1
]}

Chen, Xiang-Yu ^{[1
]}

Sun, Li-hui ^{[1
]}

Ye, Song ^{[1
]}

机构：

[1] Chinese Acad Sci, Inst Chem, Beijing Natl Lab Mol Sci, CAS Key Lab Mol Recognit & Funct, Beijing 100190, Peoples R China

来源：

JOURNAL OF ORGANIC CHEMISTRY | 2010年 / 75卷 / 20期

基金：

美国国家科学基金会;

关键词：

DIELS-ALDER REACTIONS; NUCLEOPHILIC CARBENES; GAMMA-BUTYROLACTONES; ASYMMETRIC-SYNTHESIS; ACID-DERIVATIVES; ALPHA; ALDEHYDES; FUNCTIONALIZATION; HETEROCYCLES; CHEMISTRY;

D O I：

10.1021/jo101318u

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Chiral N-heterocyclic carbenes were found to be efficient catalysts for the formal [4+2] cycloaddition reaction of alkyl(aryl)ketenes and 3-alkylenyloxindoles to give the corresponding 3 4-dihydropyrano[2,3-b]indol-2-ones in excellent yields with good diastero- and enantioselectivites in excellent

引用

页码：6973 / 6976

页数：4

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