P-Stereogenic pincer iridium complexes: Synthesis, structural characterization and application in asymmetric hydrogenation

被引：23
|
作者：
Yang, Zehua [1 ]
Wei, Xuan [1 ]
Liu, Delong [1 ]
Liu, Yangang [1 ]
Sugiya, Masashi [3 ]
Imamoto, Tsuneo [3 ,4 ]
Zhang, Wanbin [1 ,2 ]
机构：
[1] Shanghai Jiao Tong Univ, Sch Pharm, Shanghai 200240, Peoples R China
[2] Shanghai Jiao Tong Univ, Sch Chem & Chem Engn, Shanghai 200240, Peoples R China
[3] Nippon Chem Ind Co Ltd, Organ R&D Dept, Koto Ku, Tokyo 1368515, Japan
[4] Chiba Univ, Grad Sch Sci, Dept Chem, Inage Ku, Chiba 2638522, Japan
来源：
JOURNAL OF ORGANOMETALLIC CHEMISTRY | 2015年 / 791卷
基金：
中国国家自然科学基金;
关键词：
P-Stereogenic phosphine ligand; Pincer iridium complex; Asymmetric hydrogenation; CHIRAL PHOSPHINE-LIGANDS; EFFICIENT HYDROGENATION; CARBON-DIOXIDE; PYBOX; DIARYLPHOSPHINES; TRANSFORMATION; REACTIVITY; REDUCTION; ALKYNES; ENONES;
D O I：
10.1016/j.jorganchem.2015.05.002
中图分类号：
O61 [无机化学];
学科分类号：
070301 ; 081704 ;
摘要：
P-Stereogenic PNP type pincer iridium complexes (PNPIrH2Cl)-Ir-tBuMe (3) and (PNPIrH3)-Ir-tBuMe (4) were synthesized in reasonable yields and characterized by H-1 NMR, C-13 NMR, P-31 NMR, HRMS and/or single crystal X-ray diffraction. The ORTEP diagram shows that the coordination geometry around the iridium center of complex 3 is approximately octahedral. The chlorinated iridium complex (3) and/or the trihydride iridium complex (4) were used as catalysts in the asymmetric hydrogenation of ketones, olefins and quinoline to provide the desired products with up to 17% enantioselectivity. (C) 2015 Elsevier B.V. All rights reserved.
引用
收藏
页码：41 / 45
页数：5
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