Advances in Treatment Models of Advanced Gastric Cancer

被引:5
|
作者
Li, Tao [1 ]
He, Yufang [2 ]
Zhong, Qinglei [2 ]
Yu, Jiang [1 ]
Chen, Xinhua [1 ]
机构
[1] Southern Med Univ, Nanfang Hosp, Dept Gen Surg, Guangzhou 510515, Peoples R China
[2] Southern Med Univ, Clin Med Sch 1, Guangzhou, Guangdong, Peoples R China
关键词
gastric cancer; cancer treatment; chemotherapy; HIPEC; conversion therapy; molecular-targeted therapy; GASTROESOPHAGEAL JUNCTION CANCER; INTRAPERITONEAL AEROSOL CHEMOTHERAPY; LONG-TERM SURVIVAL; DOUBLE-BLIND; NEOADJUVANT CHEMOTHERAPY; OPEN-LABEL; PHASE-II; 1ST-LINE THERAPY; COMBINATION CHEMOTHERAPY; CONVERSION THERAPY;
D O I
10.1177/15330338221090353
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
The prognosis of advanced gastric cancer (AGC) is extremely poor, and the therapeutic effect of traditional palliative chemotherapy is far from satisfactory. To overcome this bottleneck, palliative surgery resection, perioperative chemotherapy combined with surgical resection, hyperthermic intraperitoneal chemotherapy (HIPEC), pressurized intraperitoneal aerosol chemotherapy (PIPAC), radiation therapy, molecular-targeted therapy have been explored in AGC. Although considerable progress has been achieved, there is still no overwhelming therapeutic method. Due to the high heterogeneity of AGC, it is particularly vital to reshaped the paradigm of gastric cancer therapy according to the characteristics of clinical classifications and molecular subtypes.
引用
收藏
页数:10
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