Serious rash after prolonged use of lamotrigine - report of four cases

被引：0

作者：

Bozic, Ksenija ^{[1
]}

Gebauer-Bukurov, Ksenija

Jovanovic, Marina

Vujanovic, Ljuba ^{[2
]}

Slankamenac, Petar

机构：

[1] Clin Ctr Vojvodina, Neurol Clin, Dept Epilepsy & Child Neurol, Novi Sad, Serbia

[2] Clin Ctr Vojvodina, Dermatol Clin, Novi Sad, Serbia

来源：

HEALTHMED | 2011年 / 5卷 / 02期

关键词：

antiepileptic drugs; lamotrigine; drug hypersensitivity skin reaction; DRUG; EPILEPSY; SAFETY; SKIN;

D O I：

暂无

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Hypersensitivity reactions related to antiepileptic drugs usually occur within the first two months after initiation of therapy. We describe four patients who developed late allergic reaction on the skin after prolonged exposure to lamotrigine monotherapy, from among about 500 patients treated with this drug in our center. Their reaction was severe enough to require discontinuation of the lamotrigine. Hypersensitivity reaction related to the administration of LTG was confirmed not only clinically but also by allergological tests.

引用

页码：425 / 428

页数：4

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