Knockdown of phospholamban using antisense oligonucleotides halts disease progression and resolves protein aggregation in mice with advanced phospholamban p.Arg14del cardiomyopathy

被引：0

作者：

Eijgenraam, T. R. ^{[1
]}

Stege, N. M. ^{[1
]}

Teixeira, V. Oliveira Nunes ^{[1
]}

Beverborg, N. Grote ^{[1
]}

Spaeter, D. ^{[2
]}

Knoell, R. ^{[2
]}

Hansson, K. M. ^{[2
]}

Amilon, C. ^{[2
]}

Janzen, D. ^{[2
]}

Yeh, S. T. ^{[3
]}

Mullick, A. E. ^{[3
]}

Van der Meer, P.

De Boer, R. A.

Sillje, H. H. W.

机构：

[1] Univ Med Ctr Groningen, Cardiol, Groningen, Netherlands

[2] AstraZeneca, Gothenburg, Sweden

[3] Ionis Pharmaceut, Carlsbad, CA USA

来源：

EUROPEAN JOURNAL OF HEART FAILURE | 2022年 / 24卷

关键词：

D O I：

暂无

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

引用

页码：277 / 277

页数：1

共 25 条

[21] Cardiac contractility modulation as bailout in a patient with phospholamban p.Arg14del related cardiomyopathy intolerant to medication: a case report
Verelst, Faro R.
Van Assche, Lauranne
Huybrechts, Wim
Gevaert, Andreas B.
Van Craenenbroeck, Emeline M.
EUROPEAN HEART JOURNAL-CASE REPORTS, 2025, 9 (01)
[22] INCREMENTAL VALUE OF RIGHT VENTRICULAR ENDOMYOCARDIAL BIOPSY TO THE PHENOTYPING OF PHOSPHOLAMBAN P.ARG14DEL MUTATION-RELATED CARDIOMYOPATHY
te Rijdt, Wouter P.
van der Zwaag, Paul A.
de Boer, Rudolf
Van den Berg, Maarten
van Tintelen, J. Peter
Suurmeijer, Albert J. H.
JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, 2015, 65 (10) : A933 - A933
[23] Phospholamban p.Arg14del-mutation related cardiomyopathy is a biventricular arrhythmogenic cardiomyopathy and protein-aggregate associated disease
Te Rijdt, W. P.
Van der Zwaag, P. A.
Van Tintelen, J. P.
Gho, J. M. I.
De Boer, R. A.
Van den Berg, M. P.
Van der Wal, A. C.
Vink, A.
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CARDIOVASCULAR RESEARCH, 2014, 103
[24] High Resolution Systematic Digital Histological Quantification of Cardiac Fibrosis and Adipose Tissue in Phospholamban p.Arg14del Mutation Associated Cardiomyopathy
Gho, Johannes M. I. H.
van Es, Rene
Stathonikos, Nikolas
Harakalova, Magdalena
te Rijdt, Wouter P.
Suurmeijer, Albert J. H.
van der Heijden, Jeroen F.
de Jonge, Nicolaas
Chamuleau, Steven A. J.
de Weger, Roel A.
Asselbergs, Folkert W.
Vink, Aryan
PLOS ONE, 2014, 9 (04):
[25] Improving electrocardiogram-based detection of rare genetic heart disease using transfer learning: An application to phospholamban p.Arg14del mutation carriers
Lopes, Ricardo R.
Bleijendaal, Hidde
Ramos, Lucas A.
Verstraelen, Tom E.
Amin, Ahmad S.
Wilde, Arthur A. M.
Pinto, Yigal M.
de Mol, Bas A. J. M.
Marquering, Henk A.
COMPUTERS IN BIOLOGY AND MEDICINE, 2021, 131 (131)

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