An indolizine-rhodamine based FRET fluorescence sensor for highly sensitive and selective detection of Hg2+ in living cells

被引：37

作者：

Ji, Ruixue ^{[1
]}

Liu, Aikun ^{[1
]}

Shen, Shili ^{[1
]}

Cao, Xiaoqun ^{[1
]}

Li, Fei ^{[1
]}

Ge, Yanqing ^{[1
]}

机构：

[1] Taishan Med Univ, Sch Chem & Pharmaceut Engn, Tai An 271000, Shandong, Peoples R China

来源：

RSC ADVANCES | 2017年 / 7卷 / 65期

关键词：

RESONANCE ENERGY-TRANSFER; PROBE; CHEMOSENSORS; SYSTEM; IONS; CHEMODOSIMETER; MECHANISMS; CU2+; DYAD;

D O I：

10.1039/c7ra07938a

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

An indolizine-rhodamine-based ratiometric fluorescent probe was designed and successfully synthesized. The probe shows a large Stokes shift (204 nm), high sensitivity and high selectivity. The detection limit was calculated to be as low as 8.76 nM. The probe could quickly (5 min) detect Hg2+ over a wide pH range from 5 to 10. Furthermore, it could be used for imaging Hg2+ in living cells.

引用

页码：40829 / 40833

页数：5

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