Preparation and study on the solid inclusion complex of cloxacillin sodium with β-cyclodextrin

被引：8
|
作者：
Chao, Jian-Bin [1 ]
Zhang, Bing-Tai
机构：
[1] Shanxi Univ, Inst Modern Chem, Taiyuan 030006, Peoples R China
[2] Shanxi Med Univ, Clin Hosp 2, Taiyuan 030006, Peoples R China
来源：
SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY | 2007年 / 68卷 / 01期
关键词：
cloxacillin sodium; beta-CD; inclusion complex; 1D NMR; 2D NMR;
D O I：
10.1016/j.saa.2006.10.058
中图分类号：
O433 [光谱学];
学科分类号：
0703 ; 070302 ;
摘要：
The interaction of cloxacillin sodium with beta-cyclodextrin (beta-CD) has been studied by several analytical techniques, including H-1 NMR, fluorescence spectroscopy, infrared spectroscopy. In this paper, solid inclusion complex of cloxacillin sodium with beta-CD was synthesized by the coprecipitation method. In addition, the characterization of the inclusion complex has been proved by fluorimetry, infrared spectroscopy and 1D, 2D NMR. The experimental results confirmed the existence of 1: 1 inclusion complex of cloxacillin sodium with beta-CD. The formation constant of complex was determined by fluorescence method and H-1 NMR. Spacial configuration of complex has been proposed on 2D NMR technique. (c) 2006 Elsevier B.V. All rights reserved.
引用
收藏
页码：108 / 112
页数：5
相关论文
共 50 条
  • [41] Preparation and physicochemical characterization of omeprazole:methyl-beta-cyclodextrin inclusion complex in solid state
    Figueiras, Ana
    Ribeiro, Laura
    Vieira, M. Teresa
    Veiga, Francisco
    JOURNAL OF INCLUSION PHENOMENA AND MACROCYCLIC CHEMISTRY, 2007, 57 (1-4) : 173 - 177
  • [42] Preparation and characterizations of solid/aqueous phases inclusion complex of 2,4-dinitroaniline with β-cyclodextrin
    Stalin, Thambusamy
    Srinivasan, Krishnan
    Sivakumar, Krishnamoorthy
    Radhakrishnan, S.
    CARBOHYDRATE POLYMERS, 2014, 107 : 72 - 84
  • [43] Preparation and physicochemical characterization of omeprazole:methyl-beta-cyclodextrin inclusion complex in solid state
    Ana Figueiras
    Laura Ribeiro
    M. Teresa Vieira
    Francisco Veiga
    Journal of Inclusion Phenomena and Macrocyclic Chemistry, 2007, 57 : 173 - 177
  • [44] The crystal structure of the inclusion complex of the sodium salt of piroxicam with β-cyclodextrin
    Chiesi-Villa, A
    Rizzoli, C
    Amari, G
    Delcanale, M
    Redenti, E
    Ventura, P
    SUPRAMOLECULAR CHEMISTRY, 1998, 10 (02) : 111 - 119
  • [45] Study on the preparation of geranyl acetone and β-cyclodextrin inclusion complex and its application in cigarette flavoring
    Fu Du
    Tingting Pan
    Xiaoming Ji
    Jingyan Hu
    Tianbao Ren
    Scientific Reports, 10
  • [46] Study on the preparation of geranyl acetone and β-cyclodextrin inclusion complex and its application in cigarette flavoring
    Du, Fu
    Pan, Tingting
    Ji, Xiaoming
    Hu, Jingyan
    Ren, Tianbao
    SCIENTIFIC REPORTS, 2020, 10 (01)
  • [47] Preparation of celecoxib-dimethyl-β-cyclodextrin inclusion complex:: characterization and in vitro permeation study
    Ventura, CA
    Giannone, I
    Paolino, D
    Pistará, V
    Corsaro, A
    Puglisi, G
    EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2005, 40 (07) : 624 - 631
  • [48] Preparation and Properties Study of Inclusion Complex of Triptonide with 2,6-Dimethyl-β-cyclodextrin
    Jin Wen
    Li Fei-Yang
    Huang Yu-Rong
    Yang Hui-Wen
    Chi Shao-Ming
    Zhu Hong-You
    Lei Ze
    Zhao Yan
    CHINESE JOURNAL OF ANALYTICAL CHEMISTRY, 2019, 47 (08) : 1235 - 1242
  • [49] Grinding as Solvent-Free Green Chemistry Approach for Cyclodextrin Inclusion Complex Preparation in the Solid State
    Jug, Mario
    Mura, Paola Angela
    PHARMACEUTICS, 2018, 10 (04):
  • [50] An inclusion complex of eugenol into β-cyclodextrin: Preparation, and physicochemical and antifungal characterization
    Gong, Liang
    Li, Taotao
    Chen, Feng
    Duan, Xuewu
    Yuan, Yunfei
    Zhang, Dandan
    Jiang, Yueming
    FOOD CHEMISTRY, 2016, 196 : 324 - 330
12345