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Kings Coll London, BHF Ctr Excellence, Div Imaging Sci,Rayne Inst, NIHR Biomed Res Ctr,Guys St Thomas NHS Fdn Trust, London SE1 7EH, England Kings Coll London, BHF Ctr Excellence, Div Imaging Sci,Rayne Inst, NIHR Biomed Res Ctr,Guys St Thomas NHS Fdn Trust, London SE1 7EH, England