Allogeneic Hematopoietic Stem Cell Transplantation in a Rare Case of Tonsillar Mast Cell Sarcoma

被引：6

作者：

Kubasch, Anne Sophie ^{[1
]}

Franke, Georg-Nikolaus ^{[1
]}

Aldaoud, Ali ^{[2
]}

Weibl, Konstantin ^{[1
]}

Jentzsch, Madlen ^{[1
]}

Sabri, Osama ^{[3
]}

Horny, Hans-Peter ^{[4
]}

Fend, Falko ^{[5
,6
]}

Behre, Gerhard ^{[1
]}

Platzbecker, Uwe ^{[1
]}

Vucinic, Vladan ^{[1
]}

机构：

[1] Univ Hosp Leipzig, Med Clin & Policlin Hematol & Cellular Therapy 1, Leipzig, Germany

[2] Outpatient Ctr Hematol & Oncol, Leipzig, Germany

[3] Univ Hosp Leipzig, Dept Nucl Med, Leipzig, Germany

[4] Ludwig Maximilians Univ Munchen, Inst Pathol, Munich, Germany

[5] Univ Tubingen, Inst Pathol & Neuropathol, Tubingen, Germany

[6] Univ Hosp Tuebingen, Ctr Comprehens Canc, Tubingen, Germany

来源：

FRONTIERS IN ONCOLOGY | 2020年 / 10卷

关键词：

mast cell sarcoma; allogeneic stem cell transplantation; mast cell neoplasm; rare disease (RD); poor prognosis;

D O I：

10.3389/fonc.2020.00219

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

Mast cell sarcoma comprises a rare aggressive mast cell neoplasia with histological, clinical, and genetic features distinct from other mast cell neoplasm. Until now, prognosis is still poor due to high rates of progression to mast cell leukemia and failure of conventional chemotherapies. Our here presented first report about successful allogeneic hematopoietic stem cell transplantation leading to remission in a case of tonsillar MCS represents a promising potential curative treatment option for this rare and often fatal disease.

引用

页数：4

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