A case report of angiosarcoma of the tongue is presented. The specimen revealed single and clustered large, pleomorphic, and spindle-shaped cells with a markedly hemorrhagic background. Tumor cells showed expression of thrombomodulin and E-selectin. but no expression of Factor VIII-related antigen, Ulex europaeus agglutinin-I, vascular endothelial growth factor, and CD34. In the current study, immunohistochemical results using antibodies against thrombomodulin and E-selection supported the diagnosis of angiosarcoma.
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AUO San Giovanni di Dio & Ruggi dAragona, Pathol Unit, Salerno, ItalyAUO San Giovanni di Dio & Ruggi dAragona, Pathol Unit, Salerno, Italy
D'Antonio, Antonio
Amico, Paolo
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Umberto I Hosp, Pathol Unit, I-94100 Enna, ItalyAUO San Giovanni di Dio & Ruggi dAragona, Pathol Unit, Salerno, Italy
Amico, Paolo
Luciani, Remo
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AUO San Giovanni di Dio & Ruggi dAragona, Nephrol Dialysis & Renal Transplant Unit, Salerno, ItalyAUO San Giovanni di Dio & Ruggi dAragona, Pathol Unit, Salerno, Italy
Luciani, Remo
Argentino, Salvatore
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AUO San Giovanni di Dio & Ruggi dAragona, Odontostomatol Unit, Salerno, ItalyAUO San Giovanni di Dio & Ruggi dAragona, Pathol Unit, Salerno, Italy
Argentino, Salvatore
Fraggetta, Filippo
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Cannizzaro Hosp, Pathol Unit, Catania, ItalyAUO San Giovanni di Dio & Ruggi dAragona, Pathol Unit, Salerno, Italy