Combination drug release of smart cyclodextrin-gated mesoporous silica nanovehicles

被引:25
|
作者
Zhou, Shengwang [1 ]
Sha, Huizi [2 ,3 ]
Ke, Xiaokang [1 ]
Liu, Baorui [2 ,3 ]
Wang, Xizhang [1 ]
Du, Xuezhong [1 ]
机构
[1] Nanjing Univ, State Key Lab Coordinat Chem, Sch Chem & Chem Engn, Key Lab Mesoscop Chem,Minist Educ, Nanjing 210093, Jiangsu, Peoples R China
[2] Nanjing Univ, Ctr Comprehens Canc, Drum Tower Hosp, Sch Med, Nanjing 210008, Jiangsu, Peoples R China
[3] Nanjing Univ, Clin Canc Inst, Nanjing 210008, Jiangsu, Peoples R China
基金
中国国家自然科学基金;
关键词
GUEST MOLECULES; BORONIC ACIDS; CARGO RELEASE; PH; NANOPARTICLES; DELIVERY; NANOVALVES; GLUCOSE; NANOCONTAINERS; SYSTEM;
D O I
10.1039/c5cc00585j
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
An integrated gamma-cyclodextrin-gated mesoporous silica delivery system via dual dynamic covalent bonds was constructed with dual drug loading for simultaneous and cascade release in targeted combination drug therapy.
引用
收藏
页码:7203 / 7206
页数:4
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