Minor antigen solves major problem

被引：3

作者：

Dazzi, F ^{[1
]}

Simpson, E ^{[1
]}

Goldman, JM ^{[1
]}

机构：

[1] Univ London Imperial Coll Sci Technol & Med, Dept Haematol, Sch Med, Hammersmith Hosp, London, England

来源：

NATURE MEDICINE | 2001年 / 7卷 / 07期

关键词：

D O I：

10.1038/89874

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

A mouse model for donor lymphocyte infusion reveals that a single immunodominant minor H antigen is responsible for the beneficial effects of donor T lymphocytes against host leukemia. Separating the good from the bad could mean the end of graft-versus-host disease in bone marrow transplants.

引用

页码：769 / 770

页数：2

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