Novel synthesis of (3R,4R)-4-acetoxy-3-[1′(R)-tert-butyldimethylsilyloxyethyl]azetidin-2-one:: A key intermediate for penem and carbapenem synthesis

被引：9
|
作者：
Singh, Santosh Kumar [1 ]
Singh, G. B. [1 ]
Byri, V. K. [1 ]
Satish, B. [1 ]
Dhamjewar, Ravi [1 ]
Gopalan, B. [1 ]
机构：
[1] Matrix Labs Ltd, Contract Res & Mfg, IDA Bollaram, Medak Dist 502325, Andhra Pradesh, India
来源：
SYNTHETIC COMMUNICATIONS | 2008年 / 38卷 / 03期
关键词：
camphorsultam; diastereoselective; beta-lactam; silylation;
D O I：
10.1080/00397910701651300
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
Diastereoselective synthesis of (3R,4R)-4-acetoxy-3-[1'(R)-tert-butyldimethylsilyloxyethyl] azetidin-2-one (AOSA) using (-)-D-2,10-camphorsultam as a key and recyclable chiral auxiliary is described.
引用
收藏
页码：456 / 464
页数：9
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