Tumor-specific PI3K inhibition via nanoparticle targeted delivery in head and neck squamous cell carcinoma

被引：0
|
作者：
Mizrachi, Aviram
Shamay, Yosi
Shah, Janki
Brook, Samuel I.
Soong, Joanne
Rajasekhar, Vinagolu K.
Humm, John L.
Powell, Simon N.
Baselga, Jose
Heller, Daniel A.
Haimovitz-Friedman, Adriana
Scaltriti, Maurizio
机构：
来源：
CANCER RESEARCH | 2017年 / 77卷
关键词：
D O I：
10.1158/1538-7445.AM2017-4122
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
4122
引用
收藏
页数：2
相关论文
共 50 条
  • [21] TAM family receptors in conjunction with MAPK signalling are involved in acquired resistance to PI3Kα inhibition in head and neck squamous cell carcinoma
    Kara M. Ruicci
    Jalna Meens
    Paul Plantinga
    William Stecho
    Nicole Pinto
    John Yoo
    Kevin Fung
    Danielle MacNeil
    Joe S. Mymryk
    John W. Barrett
    Christopher J. Howlett
    Paul C. Boutros
    Laurie Ailles
    Anthony C. Nichols
    Journal of Experimental & Clinical Cancer Research, 39
  • [22] Disruption of the RICTOR/mTORC2 complex enhances the response of head and neck squamous cell carcinoma cells to PI3K inhibition
    Ruicci, Kara M.
    Plantinga, Paul
    Pinto, Nicole
    Khan, Mohammed I.
    Stecho, William
    Dhaliwal, Sandeep S.
    Yoo, John
    Fung, Kevin
    MacNeil, Danielle
    Mymryk, Joe S.
    Barrett, John W.
    Howlett, Christopher J.
    Nichols, Anthony C.
    MOLECULAR ONCOLOGY, 2019, 13 (10) : 2160 - 2177
  • [23] Evaluation of co-inhibition of ErbB family kinases and PI3K for HPV-negative head and neck squamous cell carcinoma
    Geng, Xinyan
    Azarbarzin, Shirin
    Yang, Zejia
    Lapidus, Rena G.
    Fan, Xiaoxuan
    Teng, Yong
    Mehra, Ranee
    Cullen, Kevin J.
    Dan, Hancai
    ONCOLOGY REPORTS, 2025, 53 (03)
  • [24] TAM family receptors in conjunction with MAPK signalling are involved in acquired resistance to PI3Kα inhibition in head and neck squamous cell carcinoma
    Ruicci, Kara M.
    Meens, Jalna
    Plantinga, Paul
    Stecho, William
    Pinto, Nicole
    Yoo, John
    Fung, Kevin
    MacNeil, Danielle
    Mymryk, Joe S.
    Barrett, John W.
    Howlett, Christopher J.
    Boutros, Paul C.
    Ailles, Laurie
    Nichols, Anthony C.
    JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH, 2020, 39 (01)
  • [25] Context-Dependent Regulation of Peripheral Nerve Abundance by the PI3K Pathway in the Tumor Microenvironment of Head and Neck Squamous Cell Carcinoma
    Khorani, Karam
    Burkart, Sebastian
    Weusthof, Christopher
    Han, Rui
    Liang, Siyuan
    Stoegbauer, Fabian
    Hess, Jochen
    CELLS, 2024, 13 (12)
  • [26] Nanog promotes PI3K/Akt and mTOR-mediated invasion in head and neck squamous cell carcinoma
    Rahimy, Elham
    Yi, David
    Lew, Daniel
    Abhold, Eric
    Kiang, Alan
    Wang-Rodriguez, Jessica
    Ongkeko, Weg
    CANCER RESEARCH, 2012, 72
  • [27] Assessment of phosphatidylinositol-3 kinase (PI3K) as a prognostic marker in head and neck squamous cell carcinoma (HNSCC)
    Pectasides, E.
    Founztilas, G.
    Sasaki, C.
    Burtness, B.
    Psyrri, A.
    JOURNAL OF CLINICAL ONCOLOGY, 2009, 27 (15)
  • [28] TAB2 Promotes the Biological Functions of Head and Neck Squamous Cell Carcinoma Cells via EMT and PI3K Pathway
    Liu, Huijuan
    Zhang, Hui
    Fan, Haidong
    Tang, Su
    Weng, Junquan
    DISEASE MARKERS, 2022, 2022
  • [29] Susceptibility of NOTCH1 mutant head and neck squamous carcinoma to PI3K/mTOR pathway inhibition via PDK1
    Sambandam, Vaishnavi
    Frederick, Mitchell J.
    Shen, Li
    Tong, Pan
    Rao, Xiayu
    Peng, Shaohua
    Mazumdar, Tuhina
    Li, Quili
    Pickering, Curtis R.
    Myers, Jeffery N.
    Wang, Jing
    Johnson, Faye M.
    MOLECULAR CANCER RESEARCH, 2020, 18 (10) : 50 - 51
  • [30] CDK 4/6 Inhibition Overcomes Acquired and Inherent Resistance to PI3Kα Inhibition in Pre-Clinical Models of Head and Neck Squamous Cell Carcinoma
    Remer, Eric
    Badarni, Mai
    Hikri, Elad
    Dayan, Avraham
    Levi, Lirit
    Popovtzer, Aron
    Iraqi, Muhammed
    Porgador, Angel
    Joshua, Ben-Zion
    Bachar, Gideon
    Elkabets, Moshe
    Scaltriti, Maurizio
    Mizrachi, Aviram
    JOURNAL OF CLINICAL MEDICINE, 2020, 9 (10) : 1 - 12
12345