dendritic cells;
vaccination;
cancer therapy;
immunotherapy;
tumour-specific vaccine;
immunologic adjuvants;
D O I:
10.1053/ctrv.2001.0221
中图分类号:
R73 [肿瘤学];
学科分类号:
100214 ;
摘要:
Dendritic cells (DC) are professional antigen-presenting cells whose primary function is the initiation of immune response. Based on the finding that the immune system usually fails to identify and kill cancer cells, DC have been recently used as vaccines for stimulation of tumour-specific immunity. This review focuses on pitfalls related to DC-based vaccination against solid tumours and on improvement of this immunotherapeutic approach for routine treatment of cancer disease. (C) 2001 Harcourt Publishers Ltd.
机构:
Icahn Sch Med Mt Sinai, Tisch Canc Inst, New York, NY 10029 USAIcahn Sch Med Mt Sinai, Tisch Canc Inst, New York, NY 10029 USA
Saxena, Mansi
Bhardwaj, Nina
论文数: 0引用数: 0
h-index: 0
机构:
Icahn Sch Med Mt Sinai, Tisch Canc Inst, New York, NY 10029 USA
Parker Inst Canc Immunotherapy, San Francisco, CA 94129 USAIcahn Sch Med Mt Sinai, Tisch Canc Inst, New York, NY 10029 USA