Dendritic cell vaccines for cancer therapy

被引：19
|
作者：
Sprinzl, GM
Kacani, L
Schrott-Fischer, A
Romani, N
Thumfart, WF
机构：
[1] Univ Innsbruck, Hals Nasen Ohren Klin, Dept Otolaryngol Head & Neck Surg, A-6020 Innsbruck, Austria
[2] Univ Innsbruck, Inst Hyg & Social Med, A-6020 Innsbruck, Austria
[3] Univ Innsbruck, Dept Dermatol, A-6020 Innsbruck, Austria
来源：
CANCER TREATMENT REVIEWS | 2001年 / 27卷 / 04期
关键词：
dendritic cells; vaccination; cancer therapy; immunotherapy; tumour-specific vaccine; immunologic adjuvants;
D O I：
10.1053/ctrv.2001.0221
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
Dendritic cells (DC) are professional antigen-presenting cells whose primary function is the initiation of immune response. Based on the finding that the immune system usually fails to identify and kill cancer cells, DC have been recently used as vaccines for stimulation of tumour-specific immunity. This review focuses on pitfalls related to DC-based vaccination against solid tumours and on improvement of this immunotherapeutic approach for routine treatment of cancer disease. (C) 2001 Harcourt Publishers Ltd.
引用
收藏
页码：247 / 255
页数：9
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