Obesity as a Risk Factor for Severe COVID-19 in Hospitalized Patients: Epidemiology and Potential Mechanisms

被引：8

作者：

Aburto, Scarleth ^{[1
]}

Cisterna, Mischka ^{[1
]}

Acuna, Javiera ^{[1
]}

Ruiz, Camila ^{[1
]}

Viscardi, Sharon ^{[1
,2
,3
]}

Marquez, Jose Luis ^{[4
]}

Villano, Ines ^{[5
]}

Letelier, Pablo ^{[1
]}

Guzman, Neftali ^{[1
]}

机构：

[1] Univ Catolica Temuco, Fac Ciencias Salud, Dept Proc Diagnost & Evaluac, Lab Invest Salud Precis, Temuco 4780000, Chile

[2] Univ Catolica Temuco, Nucleo Invest Prod Alimentaria, Temuco 4780000, Chile

[3] Biotechnol Funct Foods Lab, Camino Sanquilco,Parcela 18, Padre Las Casas 4850000, Chile

[4] Univ Santiago Chile, Fac Ciencias Med, Escuela Kinesiol, Santiago 9160000, Chile

[5] Univ Campania Luigi Vanvitelli, Dipartimento Med Sperimentale, I-81100 Caserta, Italy

来源：

HEALTHCARE | 2022年 / 10卷 / 10期

关键词：

COVID-19; SARS-COV-2; infection; obesity; SARS-COV-2; IMPACT; OUTCOMES;

D O I：

10.3390/healthcare10101838

中图分类号：

R19 [保健组织与事业（卫生事业管理）];

学科分类号：

摘要：

SARS-CoV-2 infection is a global public health problem, causing significant morbidity and mortality. Evidence shows that obesity is a recognized risk factor for hospitalization, admission to critical care units, and the development of serious complications from COVID-19. This review analyzes the available epidemiological evidence that relates obesity to a higher risk of severity and mortality from COVID-19, examining the possible pathophysiological mechanisms that explain this phenomenon on a cellular and molecular level.

引用

页数：10

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