In order to improve the efficiency of seat design and enhance the safety of vehicle seats, it is necessary to carry out CAE analysis on seat safety before making physical tests. In this paper, the finite element analysis theory and HyperWorks finite element analysis software are applied in the pretreatment of vehicle seats, seat belts, as well as the upper limbs and buttocks of dummies. The loading time and load of the seat are set according to GB 14167-2013 of the People's Republic of China, and CAE calculation is carried out based on LS-DYNA software, obtaining the stress-strain nephogram of the corresponding vehicle seats. An improved scheme is proposed base on the analysis results, and CAE analysis is carried out on the improved seats again. The results of the analysis fully meet the national standard GB 14167-2013 and material strength requirements, which are of important guiding significance in reducing the development costs, shortening the development cycle and improving the passing rate of physical test.