A Markovian approach to the control of genetic regulatory networks

被引：29
|
作者：
Chen, Peter C. Y. [1 ]
Chen, Jeremy W. [1 ]
机构：
[1] Natl Univ Singapore, Fac Engn, Dept Mech Engn, Singapore 117548, Singapore
来源：
BIOSYSTEMS | 2007年 / 90卷 / 02期
关键词：
genetic networks; Markov chains; minimum-cost control; heuristic;
D O I：
10.1016/j.biosystems.2006.12.005
中图分类号：
Q [生物科学];
学科分类号：
07 ; 0710 ; 09 ;
摘要：
This paper presents an approach for controlling gene networks based on a Markov chain model, where the state of a gene network is represented as a probability distribution, while state transitions are considered to be probabilistic. An algorithm is proposed to determine a sequence of control actions that drives (without state feedback) the state of a given network to within a desired state set with a prescribed minimum or maximum probability. A heuristic is proposed and shown to improve the efficiency of the algorithm for a class of genetic networks. (c) 2007 Elsevier Ireland Ltd. All rights reserved.
引用
收藏
页码：535 / 545
页数：11
相关论文
共 50 条
  • [21] State estimation for delayed genetic regulatory networks with reaction diffusion terms and Markovian jump
    Chengye Zou
    Changjun Zhou
    Qiang Zhang
    Xinyu He
    Chun Huang
    Complex & Intelligent Systems, 2023, 9 : 5297 - 5311
  • [22] State estimation for delayed genetic regulatory networks with reaction diffusion terms and Markovian jump
    Zou, Chengye
    Zhou, Changjun
    Zhang, Qiang
    He, Xinyu
    Huang, Chun
    COMPLEX & INTELLIGENT SYSTEMS, 2023, 9 (05) : 5297 - 5311
  • [23] Controllability of Markovian jump Boolean control networks: A graphical approach
    Zhang, Qingle
    Feng, Jun-e
    Zhao, Peixin
    NEUROCOMPUTING, 2022, 498 : 89 - 97
  • [24] Disturbance Attenuation Analysis for Markovian Jump Genetic Regulatory Networks with Mode Dependent Delays
    Mohamadian, Mohammad
    Abolmasoumi, Amir Hossein
    Momeni, Hamid Reza
    2011 CHINESE CONTROL AND DECISION CONFERENCE, VOLS 1-6, 2011, : 3131 - 3136
  • [25] Robust Stability of Markovian Jumping Genetic Regulatory Networks with Mode-Dependent Delays
    He, Guang
    Fang, Jian-An
    Wu, Xiaotai
    MATHEMATICAL PROBLEMS IN ENGINEERING, 2012, 2012
  • [26] Robust asymptotic stability of fuzzy Markovian jumping genetic regulatory networks with time-varying delays by delay decomposition approach
    Balasubramaniam, P.
    Sathy, R.
    COMMUNICATIONS IN NONLINEAR SCIENCE AND NUMERICAL SIMULATION, 2011, 16 (02) : 928 - 939
  • [27] Soft Computing Approach for Modeling Genetic Regulatory Networks
    Raza, Khalid
    Parveen, Rafat
    ADVANCES IN COMPUTING AND INFORMATION TECHNOLOGY, VOL 3, 2013, 178 : 1 - 11
  • [28] Control of internal and external noise in genetic regulatory networks
    Orrell, D
    Bolouri, H
    JOURNAL OF THEORETICAL BIOLOGY, 2004, 230 (03) : 301 - 312
  • [29] Recent Advances in Intervention in Markovian Regulatory Networks
    Faryabi, Babak
    Vahedi, Golnaz
    Datta, Aniruddha
    Chamberland, Jean-Francois
    Dougherty, Edward R.
    CURRENT GENOMICS, 2009, 10 (07) : 463 - 477
  • [30] Robust control of uncertain nonlinear switched genetic regulatory networks with time delays: A redesign approach
    Moradi, Hojjatullah
    Majd, Vahid Johari
    MATHEMATICAL BIOSCIENCES, 2016, 275 : 10 - 17
12345