Ion implantation inhibits cell attachment to glassy polymeric carbon

被引：3

作者：

Zimmerman, R.

Deliloglu-Gurhan, I.

Ozdal-Kurt, F.

Sen, B. H.

Rodrigues, M.

Ila, D.

机构：

[1] Alabama A&M Univ, Ctr Irradiat Mat, Normal, AL 35762 USA

[2] Ege Univ, Fac Engn, Izmir, Turkey

[3] Celal Bayar Univ, Fac Sci, Manisa, Turkey

[4] Ege Univ, Fac Dent, Izmir, Turkey

[5] Univ Sao Paulo, BR-14049 Ribeirao Preto, SP, Brazil

来源：

NUCLEAR INSTRUMENTS & METHODS IN PHYSICS RESEARCH SECTION B-BEAM INTERACTIONS WITH MATERIALS AND ATOMS | 2007年 / 261卷 / 1-2期

基金：

美国国家科学基金会;

关键词：

carbon biocompatibility; cell adhesion;

D O I：

10.1016/j.nimb.2007.04.196

中图分类号：

TH7 [仪器、仪表];

学科分类号：

0804 ; 080401 ; 081102 ;

摘要：

Implantation of MeV gold, oxygen, carbon ions into GPC alters the surface topography of GPC and enhances the already strong tendency for cells to attach to GPC. We have shown that implantation of silver ions near the surface strongly inhibits cell growth on GPC. Both enhanced adhesion of and inhibition of cell growth are desirable improvements on cardiac implants that have long been successfully fabricated from biocompatible glassy polymeric carbon (GPC). In vitro biocompatibility tests have been carried out with model cell lines to demonstrate that ion beam assisted deposition (IBAD) of silver, as well as silver ion bombardment, can favorably influence the surface of GPC for biomedical applications. (c) 2007 Elsevier B.V. All rights reserved.

引用

页码：760 / 762

页数：3

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