Nickel-catalyzed hydrogen-borrowing strategy: chemo-selective alkylation of nitriles with alcohols

被引:49
|
作者
Bera, Sourajit [1 ]
Bera, Atanu [1 ]
Banerjee, Debasis [1 ]
机构
[1] Indian Inst Technol Raarkee, Lab Catalysis & Organ Synth, Dept Chem, Raarkee 247667, Uttarakhand, India
关键词
ONE-POT SYNTHESIS; ALPHA-ALKYLATION; ARYLACETONITRILES; MONOALKYLATION; ACETONITRILE; HYDROTALCITE; EFFICIENT; ACCESS;
D O I
10.1039/d0cc02261f
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
The first nickel-catalyzed hydrogen-borrowing alkylation of a series of aryl acetonitriles with a variety of aryl, heteroaryl, allylic and alkyl alcohols releasing water as the by-product (>33 examples, up to 90% yield) is reported.
引用
收藏
页码:6850 / 6853
页数:4
相关论文
共 50 条
  • [21] Titanium-Catalyzed Selective N-Alkylation of Amines with Alcohols via Borrowing Hydrogen Methodology
    Upadhyay, Rahul
    Maurya, Sushil K.
    JOURNAL OF ORGANIC CHEMISTRY, 2023, 88 (24): : 16960 - 16966
  • [22] NICKEL-CATALYZED ASYMMETRIC ALKYLATION OF SOME CHIRAL AND ACHIRAL ALLYLIC ALCOHOLS
    CONSIGLIO, G
    MORANDINI, F
    PICCOLO, O
    HELVETICA CHIMICA ACTA, 1980, 63 (04) : 987 - 989
  • [23] Cobalt-Catalyzed Alkylation of Secondary Alcohols with Primary Alcohols via Borrowing Hydrogen/Hydrogen Autotransfer
    Freitag, Frederik
    Irrgang, Torsten
    Kempe, Rhett
    CHEMISTRY-A EUROPEAN JOURNAL, 2017, 23 (50) : 12110 - 12113
  • [24] Ruthenium-Catalyzed Synthesis of α-Alkylated Ketones and Quinolines in an Aqueous Medium via a Hydrogen-Borrowing Strategy Using Ketones and Alcohols
    Verma, Ashutosh
    Hazra, Susanta
    Dolui, Pritam
    Elias, Anil J.
    ASIAN JOURNAL OF ORGANIC CHEMISTRY, 2021, 10 (03) : 626 - 633
  • [25] Nickel-Catalyzed Alkylation or Reduction of Allylic Alcohols with Alkyl Grignard Reagents
    Yang, Bo
    Wang, Zhong-Xia
    JOURNAL OF ORGANIC CHEMISTRY, 2020, 85 (07): : 4772 - 4784
  • [26] Enantioselective Nickel-Catalyzed Cascade Borrowing Hydrogen Cyclization to Access Spirocycles
    Zhang, Hanyue
    Jia, Yixia
    CHINESE JOURNAL OF ORGANIC CHEMISTRY, 2021, 41 (04) : 1749 - 1750
  • [27] Iron-Catalyzed Borrowing Hydrogen C-Alkylation of Oxindoles with Alcohols
    Dambatta, Mubarak B.
    Polidano, Kurt
    Northey, Alexander D.
    Williams, Jonathan M. J.
    Morrill, Louis C.
    CHEMSUSCHEM, 2019, 12 (11) : 2345 - 2349
  • [28] Manganese-Catalyzed Anti-Markovnikov Hydroamination of Allyl Alcohols via Hydrogen-Borrowing Catalysis
    Das, Kuhali
    Sarkar, Koushik
    Maji, Biplab
    ACS CATALYSIS, 2021, 11 (12) : 7060 - 7069
  • [29] Nickel-Catalyzed Phosphine Free Direct N-Alkylation of Amides with Alcohols
    Das, Jagadish
    Banerjee, Debasis
    JOURNAL OF ORGANIC CHEMISTRY, 2018, 83 (06): : 3378 - 3384
  • [30] Nickel-catalyzed enantioselective allylic alkylation of lactones and lactams with unactivated allylic alcohols
    Ngamnithiporn, Aurapat
    Jette, Carina I.
    Bachman, Shoshana
    Virgil, Scott C.
    Stoltz, Brian M.
    CHEMICAL SCIENCE, 2018, 9 (09) : 2547 - 2551