Escherichia coli ribosomal RNA transcription:: regulatory roles for ppGpp, NTPs, architectural proteins and a polymerase-binding protein

被引：62
|
作者：
Gralla, JD [1 ]
机构：
[1] Univ Calif Los Angeles, Dept Chem & Biochem, Los Angeles, CA 90095 USA
[2] Univ Calif Los Angeles, Inst Mol Biol, Los Angeles, CA 90095 USA
来源：
MOLECULAR MICROBIOLOGY | 2005年 / 55卷 / 04期
关键词：
D O I：
10.1111/j.1365-2958.2004.04455.x
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
Ribosomal RNA transcription can limit the rate of Escherichia coli growth and is subject to complex regulation. Somehow, the cell is able to sense the general nutritional environment and adjust rRNA transcription so that an appropriate number of ribosomes is produced. This review discusses the current state of affairs, including recent information about the involvement of two nucleotide regulators, two architectural protein regulators, one new co-regulator and stalled ribosomes.
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页码：973 / 977
页数：5
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