Synthesis of activated 3-substituted indoles: an optimised one-pot procedure

被引：45

作者：

Pchalek, K ^{[1
]}

Jones, AW ^{[1
]}

Wekking, MMT ^{[1
]}

Black, DS ^{[1
]}

机构：

[1] Univ New S Wales, Sch Chem, Sydney, NSW 2052, Australia

来源：

TETRAHEDRON | 2005年 / 61卷 / 01期

基金：

澳大利亚研究理事会;

关键词：

indoles; haloketones; lithium bromide; electrophilic substitution;

D O I：

10.1016/j.tet.2004.10.060

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

3-Substituted-4,6-dimethoxyindoles can be synthesised in a one-pot procedure from 3,5-dimethoxyaniline and 2-haloketones in the presence of lithium bromide and sodium bicarbonate. (C) 2004 Elsevier Ltd. All rights reserved.

引用

页码：77 / 82

页数：6

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