Synthesis of activated 3-substituted indoles: an optimised one-pot procedure

被引：45
|
作者：
Pchalek, K [1 ]
Jones, AW [1 ]
Wekking, MMT [1 ]
Black, DS [1 ]
机构：
[1] Univ New S Wales, Sch Chem, Sydney, NSW 2052, Australia
来源：
TETRAHEDRON | 2005年 / 61卷 / 01期
基金：
澳大利亚研究理事会;
关键词：
indoles; haloketones; lithium bromide; electrophilic substitution;
D O I：
10.1016/j.tet.2004.10.060
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
3-Substituted-4,6-dimethoxyindoles can be synthesised in a one-pot procedure from 3,5-dimethoxyaniline and 2-haloketones in the presence of lithium bromide and sodium bicarbonate. (C) 2004 Elsevier Ltd. All rights reserved.
引用
收藏
页码：77 / 82
页数：6
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