Vistriterpenoids A and B, Two New 24-Nor-oleanane Triterpenoids from Dodonaea viscosa

被引：5

作者：

Wang, Xiao-Hang ^{[1
]}

Zhu, Ke-Xin ^{[2
,3
]}

Li, Jing-Ya ^{[2
]}

Lei, Chun ^{[1
]}

Hou, Ai-Jun ^{[1
]}

机构：

[1] Fudan Univ, Dept Pharmacognosy, Sch Pharm, Shanghai 201203, Peoples R China

[2] Chinese Acad Sci, Shanghai Inst Mat Med, State Key Lab Drug Res, Natl Ctr Drug Screening, Shanghai 201203, Peoples R China

[3] Univ Chinese Acad Sci, 19 A Yuquan Rd, Beijing 100049, Peoples R China

来源：

CHEMISTRY & BIODIVERSITY | 2018年 / 15卷 / 11期

基金：

中国国家自然科学基金;

关键词：

Dodonaea viscosa; vistriterpenoids A and B; triterpenoids; protein tyrosine phosphatase 1b (PTP1B); PTP1B inhibitors; inhibitory activity; CONSTITUENTS; INHIBITOR;

D O I：

10.1002/cbdv.201800426

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Two new triterpenoids, vistriterpenoids A (1) and B (2), and four known ones, were acquired from Dodonaea viscosa. Compounds 1 and 2 represent the 24-nor-oleanane triterpenoids isolated from the genus Dodonaea for the first time. Their structures were identified based on extensive spectroscopic methods. Compounds 1, 2, 5, and 6 exerted inhibitory activities against PTP1B in vitro.

引用

页数：5

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