Cross-couplings of alkyl electrophiles under "ligandless" conditions: Negishi reactions of organozirconium reagents

被引：76
|
作者：
Wiskur, SL [1 ]
Korte, A [1 ]
Fu, GC [1 ]
机构：
[1] MIT, Dept Chem, Cambridge, MA 02139 USA
来源：
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY | 2004年 / 126卷 / 01期
关键词：
D O I：
10.1021/ja0393729
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
This report establishes that simple, "ligandless" palladium complexes can catalyze the first zirconium-Negishi reactions of alkyl electrophiles. In view of the attractiveness of ligandless catalysts (cost, simplicity, and ease of purification), these observations add a significant and intriguing new dimension to the development of effective palladium-based processes for coupling alkyl electrophiles. Copyright © 2004 American Chemical Society.
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收藏
页码：82 / 83
页数：2
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