Experimental infection of dogs with highly pathogenic avian influenza virus (H5N8)

被引：10

作者：

Yuk, Seong-Su ^{[1
]}

Lee, Dong-Hun ^{[1
]}

Park, Jae-Keun ^{[1
]}

Tseren-Ochir, Erdene-Ochir ^{[1
]}

Kwon, Jung-Hoon ^{[1
]}

Noh, Jin-Yong ^{[1
]}

Song, Chang-Seon ^{[1
]}

机构：

[1] Konkuk Univ, Avian Dis Lab, Coll Vet Med, Seoul 05029, South Korea

来源：

JOURNAL OF VETERINARY SCIENCE | 2017年 / 18卷

关键词：

animal experiment; dogs; influenza A virus H5N8 subtype; transmission; virulence; A H5N1; TRANSMISSION;

D O I：

10.4142/jvs.2017.18.S1.381

中图分类号：

S85 [动物医学（兽医学）];

学科分类号：

0906 ;

摘要：

During the highly pathogenic avian influenza (HPAI) H5N8 virus outbreak in Korea, a dog in layer farm contaminated by H5N8 was reported seropositive for HPAI H5N8. To investigate the possibility of adaptation and transmission of HPAI H5N8 to dogs, we experimentally inoculated dogs with H5N8. Viral genes were weakly detected in nasal swabs and seroconversions in inoculated and contact dogs. Although the H5N8 virus did not induced severe clinical signs to dogs, the results suggest that surveillance of farm dogs should continue as a species in which the avian influenza virus may acquire infectivity to mammals through frequent contact with the virus.

引用

页码：381 / 384

页数：4

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