Gastrointestinal dysfunction in Parkinson's disease

被引:188
|
作者
Pfeiffer, Ronald F. [1 ]
机构
[1] Univ Tennessee, Hlth Sci Ctr, Dept Neurol, Memphis, TN 38163 USA
关键词
Gastrointestinal dysfunction; Dysphagia; Gastroparesis; Constipation; Anorectal dysfunction; Parkinson's disease; MULTIPLE SYSTEM ATROPHY; ENTERIC NERVOUS-SYSTEM; COLONIC TRANSIT-TIME; BOTULINUM TOXIN; RESPONSE FLUCTUATIONS; ANORECTAL FUNCTION; LEWY BODIES; SWALLOWING DISORDERS; ORAL-HEALTH; CRICOPHARYNGEAL DYSFUNCTION;
D O I
10.1016/j.parkreldis.2010.08.003
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
In recent years, an increasingly detailed picture of gastrointestinal dysfunction in the setting of Parkinson's disease has emerged. Abnormalities of function may occur at virtually all levels of the gastrointestinal tract. Weight loss, dental deterioration, salivary excess, dysphagia, gastroparesis, decreased bowel movement frequency, and anorectal dysfunction all may occur. The pathophysiologic basis for this dysfunction entails both central and enteric nervous system involvement. (C) 2010 Elsevier Ltd. All rights reserved.
引用
收藏
页码:10 / 15
页数:6
相关论文
共 50 条
  • [41] Characterization of the gastrointestinal dysfunction in the 6-hydroxydopamine rat model of Parkinson's disease
    Chai, X.
    Diwakarla, S.
    Pustovit, R.
    McQuade, R.
    Di Natale, M.
    Ermine, C.
    Parish, C.
    Finkelstein, D.
    Furness, J.
    MOVEMENT DISORDERS, 2019, 34 : S629 - S629
  • [42] Gastrointestinal Dysfunction in Parkinson's Disease: Neuro-Gastroenterology Perspectives on a Multifaceted Problem
    Tan, Ai Huey
    Chuah, Kee Huat
    Beh, Yuan Ye
    Schee, Jie Ping
    Mahadeva, Sanjiv
    Lim, Shen-Yang
    JOURNAL OF MOVEMENT DISORDERS, 2023, 16 (02) : 138 - 151
  • [43] Parkinson's disease and the gastrointestinal microbiome
    Lubomski, Michal
    Tan, Ai Huey
    Lim, Shen-Yang
    Holmes, Andrew J.
    Davis, Ryan L.
    Sue, Carolyn M.
    JOURNAL OF NEUROLOGY, 2020, 267 (09) : 2507 - 2523
  • [44] Gastrointestinal Features of Parkinson’s Disease
    Leslie J. Cloud
    James G. Greene
    Current Neurology and Neuroscience Reports, 2011, 11 : 379 - 384
  • [45] Gastrointestinal Features of Parkinson's Disease
    Cloud, Leslie J.
    Greene, James G.
    CURRENT NEUROLOGY AND NEUROSCIENCE REPORTS, 2011, 11 (04) : 379 - 384
  • [46] Gastrointestinal disorders in Parkinson's disease
    Nieuwenhuijs, VB
    Bloem, BR
    POSTGRADUATE MEDICAL JOURNAL, 1997, 73 (864) : 686 - 686
  • [47] The gastrointestinal tract and Parkinson's disease
    Higinbotham, Alissa S.
    Kilbane, Camilla W.
    FRONTIERS IN CELLULAR AND INFECTION MICROBIOLOGY, 2024, 13
  • [48] Parkinson’s disease and the gastrointestinal microbiome
    Michal Lubomski
    Ai Huey Tan
    Shen-Yang Lim
    Andrew J. Holmes
    Ryan L. Davis
    Carolyn M. Sue
    Journal of Neurology, 2020, 267 : 2507 - 2523
  • [49] Gastrointestinal Manifestations in Parkinson's Disease Using a Validated Arabic Version of Gastrointestinal Dysfunction Scale: A Multicenter Study
    Shalash, Ali Soliman
    Badr, Marwa Yassien
    Salah, Yara
    Elgamal, Shimaa
    Elaidy, Shaimaa Ahmed
    Elhamrawy, Eman Abdel-Mageed
    Abdel-Tawab, Hayam
    Hamid, Eman
    El-Seidy, Ehab Ahmed
    Dawood, Noha Lotfy
    Egyptian Parkinson Res Grp
    MOVEMENT DISORDERS CLINICAL PRACTICE, 2025,
  • [50] Gastrointestinal dysfunction in idiopathic Parkinson's disease [Gastrointestinale Störungen beim idiopathischen Parkinson-Syndrom]
    Del Tredici K.
    Jost W.H.
    Der Nervenarzt, 2012, 83 (10) : 1282 - 1291