Anti-acetylcholine receptor antibodies: effect of immunosuppressive drug therapy in patients with myasthenia gravis

被引：0
|
作者：
Sidnev, D. V. [1 ]
Sanadze, A. G. [1 ]
Dedaev, S. I. [1 ]
Karganov, M. Yu. [1 ]
Alchinova, I. B. [1 ]
机构：
[1] Moscow Myasthen Ctr, Moscow, Russia
来源：
ZHURNAL NEVROLOGII I PSIKHIATRII IMENI S S KORSAKOVA | 2010年 / 110卷 / 11期
关键词：
myasthenia gravis; anti-acetylcholine receptor antibody; immunosuppressive treatment; thymectomy; ACETYLCHOLINE-RECEPTOR; THYMECTOMY; AUTOANTIBODIES; TE671;
D O I：
暂无
中图分类号：
R74 [神经病学与精神病学];
学科分类号：
摘要：
We studied anti-acetylcholine receptor antibodies (ARAb) in 25 patients with myasthenia gravis before and after the immunosuppressive drug (steroid) therapy and in 22 patients before and after thymectomy. The clinical effect after the treatment was correlated with the reduction of ARAb levels by more than 20% in 62% of patients. The ARAb levels did not change, or even increased, in 15% patients despite the improvement of their clinical state. We showed the direct correlation between the clinical improvement and the decrease of ARAb level.
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页码：37 / 40
页数：4
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