Different informativeness of the three hypervariable mitochondrial DNA regions in the population of Bologna (Italy)

被引:22
|
作者
Bini, C
Ceccardi, S
Luiselli, D
Ferri, G
Pelotti, S
Colalongo, C
Falconi, M
Pappalardo, G
机构
[1] Univ Bologna, Dept Med & Publ Hlth, Sect Legal Med, I-40126 Bologna, Italy
[2] Univ Bologna, Sect Anthropol, Dept Biol, Bologna, Italy
关键词
mitochondrial DNA; hypervariable regions (HVRs); sequencing; polymorphism;
D O I
10.1016/S0379-0738(03)00167-1
中图分类号
DF [法律]; D9 [法律]; R [医药、卫生];
学科分类号
0301 ; 10 ;
摘要
Mitochondrial DNA (mtDNA) sequence variations at hypervariable regions HVI, HVII and HVIII were analysed in 100 unrelated Italians from Bologna. The values of the statistical parameters are in agreement with the range of European populations. We suggest that the less informative HVIII region may be useful to distinguish HVI-HVII identical sequences in forensic analysis especially when nuclear DNA cannot be investigated. (C) 2003 Elsevier Science Ireland Ltd. All fights reserved.
引用
收藏
页码:48 / 52
页数:5
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