Deficiency of cholesterol 7α hydroxylase (Cyp7a1) in bile acid synthesis exacerbates alcohol-induced liver injury in mice

被引：0
|
作者：
Donepudi, Ajay C. [1 ]
Ferrell, Jessica M. [1 ]
Boehme, Shannon M. [1 ]
Chiang, John [1 ]
机构：
[1] Northeast Ohio Med Univ, Dept Integrat Med Sci, Rootstown, OH USA
来源：
HEPATOLOGY | 2017年 / 66卷
关键词：
D O I：
暂无
中图分类号：
R57 [消化系及腹部疾病];
学科分类号：
摘要：
1978
引用
收藏
页码：1048A / 1048A
页数：1
相关论文
共 50 条
  • [31] Apolipoprotein H deficiency exacerbates alcohol-induced liver injury via gut Dysbiosis and altered bile acid metabolism
    Liu, Yaming
    Li, Tingting
    Xu, Jun
    Li, Shanshan
    Li, Binbin
    Elgozair, Mohamad
    BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS, 2024, 1869 (07):
  • [32] MECHANISM OF BILE ACID-ACTIVATED VITAMIN D RECEPTOR IN INHIBITION OF CHOLESTEROL 7α-HYDROXYLASE (CYP7A1) GENE TRANSCRIPTION IN HUMAN HEPATOCYTES
    Han, Shuxin
    Strom, Stephen C.
    Chiang, John
    HEPATOLOGY, 2009, 50 (04) : 309A - 309A
  • [33] Polyphenol Effects on Cholesterol Metabolism via Bile Acid Biosynthesis, CYP7A1: A Review
    Chambers, Karen F.
    Day, Priscilla E.
    Aboufarrag, Hassan T.
    Kroon, Paul A.
    NUTRIENTS, 2019, 11 (11)
  • [34] Differences in bile acid and cholesterol metabolism in mice expressing the human rather than the mouse CYP7A1 gene
    Cooper, A
    Lee, SJ
    Chen, J
    GASTROENTEROLOGY, 2004, 126 (04) : A748 - A748
  • [35] SEXUAL DIMORPHISM OF BILE ACID HOMEOSTASIS IN MICE DEFICIENT IN CYP7A1 AND CYP27A1
    Rizzolo, Daniel
    Kong, Bo
    Brinker, Anita
    Buckley, Brian
    Guo, Grace L.
    HEPATOLOGY, 2020, 72 : 229A - 229A
  • [36] Hepatic Deficiency of Augmenter of Liver Regeneration Exacerbates Alcohol-Induced Liver Injury and Promotes Fibrosis in Mice
    Kumar, Sudhir
    Wang, Jiang
    Rani, Richa
    Gandhi, Chandrashekhar R.
    PLOS ONE, 2016, 11 (01):
  • [37] Thyroid hormone induction of human cholesterol 7 alpha-hydroxylase (Cyp7a1) in vitro
    Lindemann, Jan A. Lammel
    Angajala, Anusha
    Engler, David A.
    Webb, Paul
    Ayers, Stephen D.
    MOLECULAR AND CELLULAR ENDOCRINOLOGY, 2014, 388 (1-2) : 32 - 40
  • [38] Cholesterol 7α-hydroxylase (CYP7A1) plays a critical role in preventing hepatic inflammation and fibrosis
    Liu, Hailiang
    Ferrell, Jessica
    Boehme, Shannon
    Chiang, John
    FASEB JOURNAL, 2016, 30
  • [39] Differential hepatocellular zonation pattern of cholesterol 7α-hydroxylase (Cyp7a1) and sterol 12α-hydroxylase (Cyp8b1) in the mouse
    Wang, Jin
    Olin, Maria
    Rozell, Bjorn
    Bjorkhem, Ingemar
    Einarsson, Curt
    Eggertsen, Gosta
    Gafvels, Mats
    HISTOCHEMISTRY AND CELL BIOLOGY, 2007, 127 (03) : 253 - 261
  • [40] Differential hepatocellular zonation pattern of cholesterol 7α-hydroxylase (Cyp7a1) and sterol 12α-hydroxylase (Cyp8b1) in the mouse
    Jin Wang
    Maria Olin
    Björn Rozell
    Ingemar Björkhem
    Curt Einarsson
    Gösta Eggertsen
    Mats Gåfvels
    Histochemistry and Cell Biology, 2007, 127 : 253 - 261
12345