HLA typing in patients with multiple evanescent white dot syndrome (MEWDS)

被引：16
|
作者：
Borruat, FX
Herbort, CP
Spertini, F
Desarnaulds, AB
机构：
[1] Hop Ophtalm Jules Gonin, CH-1004 Lausanne, Switzerland
[2] CHU Vaudois, Univ Hosp, Div Immunol & Allergy, Lausanne, Switzerland
来源：
OCULAR IMMUNOLOGY AND INFLAMMATION | 1998年 / 6卷 / 01期
关键词：
multiple evanescent white dot syndrome; HLA-B-51;
D O I：
10.1076/ocii.6.1.39.8084
中图分类号：
R77 [眼科学];
学科分类号：
100212 ;
摘要：
Background: Multiple evanescent white dot syndrome (MEWDS) is an acquired chorioretinal disorder of unknown etiology. We investigated the possibility that MEWDS might be related to a specific HLA subtying. Methods/Results: Blood was obtained from nine patients affected by MEWDS. HLA-B51 was found in four of these nine patients with MEWDS. Conclusion: There was a 3.7-fold increased frequency of HLA-B51 in patients affected by MEWDS (relative risk 5.86). MEWDS might then be related to the presence of a specific HLA subtype, HLA-B51. However, due to the small sample size, our results need to be confirmed by further testing.
引用
收藏
页码：39 / 41
页数：3
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