Glucocorticoids inhibit pancreatic β-cell development. A crucial step in the pathogenesis of type 2 diabetes?

被引：0
|
作者：
Valtat, Berangere [1 ]
Blondeau, Bertrand [1 ]
机构：
[1] Univ Paris 06, Ctr Rech Cordeliers, Inserm U872, Equipe 8, Paris, France
来源：
CORRESPONDANCES EN METABOLISMES HORMONES DIABETES ET NUTRITION | 2012年 / 16卷 / 1-2期
关键词：
Type; 2; diabetes; beta cells; Glucocorticoids; Fetal programming; MELLITUS; INSULIN; EXPOSURE; GROWTH; HUMANS;
D O I：
暂无
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
Pancreatic beta-cell function and mass play a crucial role in the progression of type 2 diabetes. Abnormal intra-uterine environment programs the alterations of adult beta-cell mass and secretory function. Glucocorticoid hormones are potent inhibitors of both beta-cell function and development.
引用
收藏
页码：32 / 35
页数：4
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