Imidazo[1,2-a]pyridine as a promising scaffold for the development of antibacterial agents

被引:11
|
作者
Mishra, Nilima Priyadarsini [1 ]
Mohapatra, Seetaram [1 ]
Das, Tapaswini [1 ]
Nayak, Sabita [1 ]
机构
[1] Ravenshaw Univ, Dept Chem, Cuttack, India
关键词
BIOLOGICAL EVALUATION; ANTIBIOTIC-RESISTANCE; ANTIMICROBIAL EVALUATION; DNA GYRASE; DERIVATIVES; POTENT; ZOLPIDEM; DESIGN; DISCOVERY; FUNCTIONALIZATION;
D O I
10.1002/jhet.4534
中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
The fascinating molecular structure and versatile bioactivity of imidazo[1,2-a]pyridine scaffold attracts the scientific community to develop new imidazo[1,2-a]pyridine based antibacterial agent in current situation. This systematic review provides a deep insight into the recent advances of imidazo[1,2-a]pyridine derivatives and its antibacterial activities from 2010 to 2021. Moreover, the structure-activity relationship and synthetic approaches are also cautiously summarized throughout the review which affords a clear vision for the medicinal chemists to design new antibacterial agents.
引用
收藏
页码:2051 / 2075
页数:25
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