The change in renal replacement therapy on acute renal failure in a general intensive care unit in a university hospital and its clinical efficacy: A Japanese experience

被引：13

作者：

Hirayama, Y ^{[1
]}

Hirasawa, H ^{[1
]}

Oda, S ^{[1
]}

Shiga, H ^{[1
]}

Nakanishi, K ^{[1
]}

Matsuda, K ^{[1
]}

Nakamura, M ^{[1
]}

Hirano, T ^{[1
]}

Moriguchi, T ^{[1
]}

Watanabe, E ^{[1
]}

Nitta, M ^{[1
]}

Abe, R ^{[1
]}

Nakada, T ^{[1
]}

机构：

[1] Chiba Univ, Grad Sch Med, Dept Emergency & Crit Care Med, Chuo Ku, Chiba 2608677, Japan

来源：

THERAPEUTIC APHERESIS AND DIALYSIS | 2003年 / 7卷 / 05期

关键词：

continuous hemodiafiltration; continuous hemofiltration; cytokine; intermittent hemodialysis; patient outcome assessment;

D O I：

10.1046/j.1526-0968.2003.00094.x

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

The aim of our study was to examine renal replacement therapies (RRT) that have been used for acute renal failure (ARF) in our intensive care unit (ICU) patients and to compare their outcomes. Sixteen patients who underwent intermittent hemodialysis (IHD), 14 patients who underwent continuous hemofiltration (CHF) in combination with IHD (CHF + IHD), and 38 patients who underwent continuous hemodiafiltration (CHDF) were evaluated. Regarding the effects of blood purification on hemodynamics and renal function, the percentage increase in blood pressure and percent rapid increase in urinary output were the greatest in the CHDF group. The hourly urinary output after the start of initial blood purification increased only in the CHDF group. The survival rate was significantly higher in the CHDF group. These results suggest that CHDF should be the first-line therapy for patients with ARF and that we are moving in the right direction regarding the application of RRT to treat ARF in ICU patients.

引用

页码：475 / 482

页数：8

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