Preparation and evaluation of shikonin ointment for wound healing - Effectiveness in an experimental wound healing model in rats

被引：0
|
作者：
Sekine, T
Kojima, K
Ota, S
Matsumoto, T
Yamamoto, T
Maitani, Y
Nagai, T
机构：
[1] Tsumura & Co, Cent Res Labs, Dept Pharmaceut Technol, Ami, Ibaraki 3001192, Japan
[2] Hoshi Univ, Dept Pharmaceut, Shinagawa Ku, Tokyo 1428501, Japan
来源：
STP PHARMA SCIENCES | 1998年 / 8卷 / 04期
关键词：
shikonin; ointment; macrogol; wound healing; deep burn; open wound;
D O I：
暂无
中图分类号：
R9 [药学];
学科分类号：
1007 ;
摘要：
Shikonin ointment was prepared Sor wound healing and its enhancing effect on wound healing was evaluated by using an experimental burn and open wound healing model in rats. The concentrations of shikonin were 0.1 and 0.5% in a macrogol base. Shikonin ointments had an enhancing effect on wound healing in the experimental burn and open wound healing models. Shikonin ointments had an anti-inflammatory effect on the experimental open wound healing model. The 0.1 % shikonin concentration was effective and the shikonin ointment was more effective on wound healing than a commercial preparation.
引用
收藏
页码：249 / 253
页数：5
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