Histopathological findings of the no-reflow phenomenon following coronary intervention for acute coronary syndrome.

被引:18
|
作者
Kawano, H
Hayashida, T
Ohtani, H
Kanda, M
Koide, Y
Baba, T
Toda, G
Shimokawa, I
Yano, K
Okada, R
机构
[1] Nagasaki Univ, Grad Sch Biomed Sci, Dept Cardiovasc Med, Course Med & Dent Sci, Nagasaki 8528501, Japan
[2] Nagasaki Univ, Grad Sch Biomed Sci, Dept Pathol, Course Med & Dent Sci, Nagasaki 8528501, Japan
[3] Gunma PAZ Coll Sch Nursing, Gunma, Japan
关键词
D O I
10.1536/ihj.46.327
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Although no-reflow phenomenon may occur in patients that experience reperfusion after ischemia, there have been no reports describing the postmortem findings in these patients. We describe the findings of an autopsy in a 56-year-old man who experienced acute coronary syndrome with no-reflow phenomenon after coronary intervention. Macroscopic study demonstrated myocardial infarction with diffuse hemorrhage, and microscopic analysis revealed vascular damage and microembolization in the no-reflow area. In conclusion, coronary microembolization and damage to the small coronary artery may contribute to the pathogenesis of no-reflow phenomenon following coronary intervention in humans.
引用
收藏
页码:327 / 332
页数:6
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