Case of plasmablastic lymphoma of the sigmoid colon and literature review

被引：9

作者：

Haramura, Tomoko ^{[1
]}

Haraguchi, Masashi ^{[1
]}

Irie, Junji ^{[2
]}

Ito, Shinichiro ^{[1
]}

Tokai, Hirotaka ^{[1
]}

Noda, Kazumasa ^{[1
]}

Kitajima, Masachika ^{[1
]}

Minami, Shigeki ^{[1
]}

Inoue, Keiji ^{[1
]}

Sasaki, Yuya ^{[3
]}

Oshima, Koichi ^{[3
]}

Eguchi, Susumu ^{[4
]}

机构：

[1] Nagasaki Harbor Med Ctr City Hosp, Dept Surg, Nagasaki 8508555, Japan

[2] Nagasaki Harbor Med Ctr City Hosp, Dept Pathol, Nagasaki 8508555, Japan

[3] Kurume Univ, Dept Pathol, Fukuoka 8300011, Japan

[4] Nagasaki Univ, Grad Sch Biomed Sci, Dept Surg, Nagasaki 8528501, Japan

来源：

WORLD JOURNAL OF GASTROENTEROLOGY | 2015年 / 21卷 / 24期

关键词：

Plasmablastic lymphoma; Sigmoid colon; Human immunodeficiency virus-negative; Immunosuppressive state; Extra-oral site; IMMUNODEFICIENCY-VIRUS-INFECTION; HIV-NEGATIVE PATIENT; ORAL-CAVITY; DIAGNOSTIC DILEMMA;

D O I：

10.3748/wjg.v21.i24.7598

中图分类号：

R57 [消化系及腹部疾病];

学科分类号：

摘要：

Plasmablastic lymphoma (PBL) is a rare form of non-Hodgkin's lymphoma that is associated with human immunodeficiency virus (HIV) infection. Although PBL is most commonly observed in the oral cavity of HIV-positive patients, it can also be observed at extra-oral sites in HIV-negative patients. This report represents an unusual case of HIV-negative PBL that occurred in the sigmoid colon. This patient had a history of systemic lupus erythematosus and an underlying immunosuppressive state from long term steroid therapy. The lymphoma cells were positive for CD138, kappa light chain restriction and Epstein-Barr virus and negative for CD20/L26, CD3, CD79a, UCHL1 (CD45RO) and cytokeratin (AE1/AE3). The patient died approximately 2 mo after the operation. In the present paper, we review cases of PBL of the colon in HIV-negative patients.

引用

页码：7598 / 7603

页数：6

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