Interleukin-6 blockade abrogates immunotherapy toxicity and promotes tumor immunity

被引:0
|
作者
Diab, A. [1 ]
Abdel-Wahab, N. [2 ]
Johnson, D. H. [3 ]
Hailemichael, Y. [1 ]
Foo, W. C. [1 ]
Bentebibel, S-E. [1 ]
Lizee, G. A. [1 ]
Ekmekcioglu, S. [1 ]
机构
[1] Univ Texas MD Anderson Canc Ctr, Melanoma Med Oncol, Houston, TX 77030 USA
[2] Univ Texas MD Anderson Canc Ctr, Gen Internal Med & Melanoma Med Oncol, Houston, TX 77030 USA
[3] Ochsner Clin Fdn, Ochsner Med Ctr, New Orleans, LA USA
关键词
D O I
10.1016/j.annonc.2021.10.090
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
72P
引用
收藏
页码:S1403 / S1403
页数:1
相关论文
共 50 条
  • [31] Interleukin-12 in anti-tumor immunity and immunotherapy
    Colombo, MP
    Trinchieri, G
    CYTOKINE & GROWTH FACTOR REVIEWS, 2002, 13 (02) : 155 - 168
  • [32] Sex and interleukin-6 are prognostic factors for autoimmune toxicity following treatment with anti-CTLA4 blockade
    Valpione, Sara
    Pasquali, Sandro
    Campana, Luca Giovanni
    Piccin, Luisa
    Mocellin, Simone
    Pigozzo, Jacopo
    Chiarion-Sileni, Vanna
    JOURNAL OF TRANSLATIONAL MEDICINE, 2018, 16
  • [33] Sex and interleukin-6 are prognostic factors for autoimmune toxicity following treatment with anti-CTLA4 blockade
    Sara Valpione
    Sandro Pasquali
    Luca Giovanni Campana
    Luisa Piccin
    Simone Mocellin
    Jacopo Pigozzo
    Vanna Chiarion-Sileni
    Journal of Translational Medicine, 16
  • [34] Interleukin-6 receptor blockade with tocilizumab to reduce immune-related toxicity with ipilimumab and nivolumab in metastatic melanoma
    Weber, Jeffrey S.
    Puranik, Amrutesh
    Mitzutani, Teruyuki
    Muramatsu, Tomoaki
    Goldberg, Judith D.
    Mehnert, Janice M.
    Li, Xiaochun
    Levinson, Benjamin A.
    Hamid, Omid
    Mehmi, Inderjit
    Faries, Mark B.
    Hodi, F. Stephen
    Buchbinder, Elizabeth Iannotti
    Ott, Patrick Alexander
    Bajwa, Sofia
    Arriola, Perla
    Legros, Naika
    Sullivan, Ryan J.
    JOURNAL OF CLINICAL ONCOLOGY, 2024, 42 (16)
  • [35] Efficient immunity against Leishmania major in the absence of interleukin-6
    Moskowitz, NH
    Brown, DR
    Reiner, SL
    INFECTION AND IMMUNITY, 1997, 65 (06) : 2448 - 2450
  • [36] INTERLEUKIN-17A PROMOTES AUTOIMMUNITY BY SYNERGIZING WITH INTERLEUKIN-6 VIA A POSITIVE- FEEDBACK LOOP OF INTERLEUKIN-6 INDUCTION IN PRIMARY ASTROCYTES
    Ma, Xiangyu
    Qin, Hongwei
    Benveniste, Etty
    NEURO-ONCOLOGY, 2009, 11 (05) : 566 - 566
  • [37] Interleukin-6 Promotes Carcinogenesis Through Multiple Signal Pathways
    Chen, Jiezhong
    Huang, Xu-Feng
    DIGESTIVE DISEASES AND SCIENCES, 2009, 54 (06) : 1373 - 1374
  • [38] Interleukin-6 promotes the dedifferentiation of papillary thyroid cancer cells
    Zhang, Guo-Qiang
    Xi, Chuang
    Shen, Chen-Tian
    Song, Hong-Jun
    Luo, Quan-Yong
    Qiu, Zhong-Ling
    ENDOCRINE-RELATED CANCER, 2023, 30 (09)
  • [39] Interleukin-6 promotes primitive endoderm development in bovine blastocysts
    Wooldridge, Lydia K.
    Ealy, Alan D.
    BMC DEVELOPMENTAL BIOLOGY, 2021, 21 (01):
  • [40] Interleukin-6 Promotes Pulmonary Emphysema Associated with Apoptosis in Mice
    Ruwanpura, Saleela M.
    McLeod, Louise
    Miller, Alistair
    Jones, Jessica
    Bozinovski, Steven
    Vlahos, Ross
    Ernst, Matthias
    Armes, Jane
    Bardin, Philip G.
    Anderson, Gary P.
    Jenkins, Brendan J.
    AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY, 2011, 45 (04) : 720 - 730