Solution of the knapsack problem by deoxyribonucleic acid computing

被引:6
|
作者
Aoi, Y
Yoshinobu, T
Tanizawa, K
Kinoshita, K
Iwasaki, H
机构
[1] Osaka Univ, Inst Sci & Ind Res, Ibaraki, Osaka 5670047, Japan
[2] Osaka Univ, Dept Appl Phys, Suita, Osaka 5650871, Japan
关键词
DNA computing; DNA; computing; knapsack problem; ligation; PCR; polymerase chain reaction;
D O I
10.1143/JJAP.37.5839
中图分类号
O59 [应用物理学];
学科分类号
摘要
Deoxyribonucleic acid (DNA) computing is executed to demonstrate that it is capable of solving a simple instance of the knapsack problem, which is known to be NP-complete. DNA molecules with different lengths coding the data are prepared, and the algorithm is implemented as molecular biological processes such as ligation,polymerase chain reaction (PCR), and DNA sequencing. The scheme of encoding, experimental procedures and results are described, and the scalability of the present method is discussed. Reactions between DNA molecules are expected to realize a massively parallel computation of the order of 10(23) per mol.
引用
收藏
页码:5839 / 5841
页数:3
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