O-Perfluoropyridin-4-yl Oximes: Iminyl Radical Precursors for Photo- or Thermal-Induced N-O Cleavage in C(sp2) C(sp3) Bond Formation

被引：37
|
作者：
Xia, Peng-Ju [1 ]
Hu, Yuan-Zhuo [1 ]
Ye, Zhi-Peng [1 ]
Li, Xu-Jie [1 ]
Xiang, Hao-Yue [1 ]
Yang, Hua [1 ,2 ]
机构：
[1] Cent South Univ, Coll Chem & Chem Engn, Changsha 410083, Peoples R China
[2] Cent South Univ, Key Lab Hunan Prov Water Environm & Agr Prod Safe, Changsha 410083, Peoples R China
来源：
JOURNAL OF ORGANIC CHEMISTRY | 2020年 / 85卷 / 05期
基金：
中国国家自然科学基金;
关键词：
C-H CYANOALKYLATION; VISIBLE-LIGHT; FACILE ACCESS; QUINOXALIN-2(1H)-ONES; CYCLIZATION; GENERATION; ALKENES; ARYLATION; CATALYSTS; CASCADE;
D O I：
10.1021/acs.joc.9b03251
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
O-Perfluoropyridin-4-yl group was first installed onto cycloketone oximes as a new electrophore, which was proven to be efficient iminyl radical precursors under photocatalytic and thermal conditions. A range of O-perfluoropyridin-4-yl oximes were successfully utilized in C(sp(2))-C(sp(3)) bond formations of quinoxalin-2(1H)-ones and alkenes, providing facile accesses to a range of functionalized alkylnitriles.
引用
收藏
页码：3538 / 3547
页数：10
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