A NEW XANTHONE DERIVATIVE FROM THE CO-CULTURE BROTH OF TWO MARINE FUNGI (STRAIN No. E33 AND K38)

被引:45
|
作者
Li, Chunyuan [1 ]
Zhang, Jie [1 ]
Shao, Changlun [2 ]
Ding, Weijiang [1 ]
She, Zhigang [3 ]
Lin, Yongcheng [3 ]
机构
[1] S China Agr Univ, Inst Biomat, Coll Sci, Guangzhou 510642, Guangdong, Peoples R China
[2] Ocean Univ China, Sch Med & Pharm, Qingdao 266003, Peoples R China
[3] Sun Yat sen Zhongshan Univ, Sch Chem & Chem Engn, Guangzhou 510275, Guangdong, Peoples R China
关键词
marine mangrove fungus; xanthone; antifungal activity;
D O I
10.1007/s10600-011-9939-8
中图分类号
R914 [药物化学];
学科分类号
100701 ;
摘要
A new xanthone derivative, 8-hydroxy-3-methyl-9-oxo-9H-xanthene-1-carboxylic acid methyl ether (1), was isolated from the co-culture broth of two mangrove fungi (strain No. K38 and E33) isolated from the South China Sea coast. The structure of 1 was determined by comprehensive spectroscopic methods, especially 2D NMR techniques. Primary bioassays showed that compound 1 has inhibitory activity against five microorganisms, including Gloeasporium musae and Peronophthora cichoralearum etc.
引用
收藏
页码:382 / 384
页数:3
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