Optical quality of the eye degraded by time-varying wavefront aberrations with tear film dynamics

Purpose: Wavefront aberrations (WFAs) of the eye vary with time because of the tear film dynamics. We investigated, using a simulation method, the variation of optical quality with time-varying wavefront measurements of 13 eyes with different refractions. Methods: WFAs of 13 normal eyes of 13 subjects were measured every second for 10s. First, we simulated WFAs with conventional corneal laser refractive surgery by subtracting the second-order aberrations of the least aberrated measurement from measured consecutive WFAs. Second, we simulated customized refractive surgery by subtracting the second- to sixth-order aberrations of the least aberrated measurement from measured consecutive WFAs. We calculated Strehl ratios and retinal images from these corrected consecutive WFAs. Results: In one eye, the root mean square (RMS) values of WFAs with a second-order correction were sometimes smaller than those of WFAs with a second- to sixth-order correction, when these were compared at the same time point after a blink. However, in the other 12 eyes, the RMS values with second- to sixth-order corrections were smaller than those with only a second-order correction. In eight eyes, the Strehl ratios with second- to sixth-order corrections were larger than those with second-order corrections. In the remaining five eyes, Strehl ratios with second- to sixth-order corrections were sometimes smaller than those with second-order corrections. Conclusions: In a simulation, the correction of time-invariant higher order aberrations usually reduced RMS values, but it did not always result in higher Strehl ratios than those obtained with only second-order corrections.