Palladium-catalyzed intermolecular alkynylcarbonylation of unactivated alkenes: easy access to β-alkynylcarboxylic esters

被引：8

作者：

Li, Xiang ^{[1
]}

Chen, Pinhong ^{[1
]}

Liu, Guosheng ^{[1
]}

机构：

[1] Chinese Acad Sci, State Key Lab OrganometChem & Shanghai Hongkong J, Ctr Excellence Mol Synth, Shanghai Inst Organ Chem,Univ Chinese Acad Sci, Shanghai 200032, Peoples R China

来源：

CHEMICAL COMMUNICATIONS | 2022年 / 58卷 / 15期

关键词：

ASYMMETRIC CONJUGATE ALKYNYLATION; TERMINAL ALKYNES; EFFICIENT ACCESS; COPPER; REACTIVITY; INHIBITORS; STRATEGY; KETONES; ENONES; EBX;

D O I：

10.1039/d1cc07092d

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

A palladium-catalyzed intermolecular alkynylcarbonylation of unactivated alkenes has been established with ethynyl benziodoxolones (EBXs) as alkynylation reagents, providing beta-alkynylcarboxylic esters efficiently from simple alkenes. The reaction features moderate to excellent regioselectivity and excellent functional group compatibility under mild reaction conditions.

引用

页码：2544 / 2547

页数：4

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