Palladium-catalyzed intermolecular alkynylcarbonylation of unactivated alkenes: easy access to β-alkynylcarboxylic esters

被引：8
|
作者：
Li, Xiang [1 ]
Chen, Pinhong [1 ]
Liu, Guosheng [1 ]
机构：
[1] Chinese Acad Sci, State Key Lab OrganometChem & Shanghai Hongkong J, Ctr Excellence Mol Synth, Shanghai Inst Organ Chem,Univ Chinese Acad Sci, Shanghai 200032, Peoples R China
来源：
CHEMICAL COMMUNICATIONS | 2022年 / 58卷 / 15期
关键词：
ASYMMETRIC CONJUGATE ALKYNYLATION; TERMINAL ALKYNES; EFFICIENT ACCESS; COPPER; REACTIVITY; INHIBITORS; STRATEGY; KETONES; ENONES; EBX;
D O I：
10.1039/d1cc07092d
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
A palladium-catalyzed intermolecular alkynylcarbonylation of unactivated alkenes has been established with ethynyl benziodoxolones (EBXs) as alkynylation reagents, providing beta-alkynylcarboxylic esters efficiently from simple alkenes. The reaction features moderate to excellent regioselectivity and excellent functional group compatibility under mild reaction conditions.
引用
收藏
页码：2544 / 2547
页数：4
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