Selective enrichment of proteins for MALDI-TOF MS analysis based on molecular imprinting

被引：43
|
作者：
Wan, Wei [1 ]
Han, Qiang [1 ]
Zhang, Xiaoqiong [1 ]
Xie, Yuming [1 ]
Sun, Jieping [1 ]
Ding, Mingyu [1 ]
机构：
[1] Tsinghua Univ, Dept Chem, Key Lab Bioorgan Phosphorus Chem & Chem Biol, Minist Educ, Beijing 100084, Peoples R China
来源：
CHEMICAL COMMUNICATIONS | 2015年 / 51卷 / 17期
关键词：
MAGNETIC NANOPARTICLES; SILICA NANOPARTICLES; RECOGNITION; MICROSPHERES; GRAPHENE; SURFACE; STABILIZATION; DOPAMINE; PEPTIDES; SIZE;
D O I：
10.1039/c4cc10205c
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
Molecularly imprinted polymers (MIPs) were applied for selective enrichment of proteins in MALDI-TOF MS analysis for the first time. MIPs were achieved simply via immobilization of template lysozyme (Lyz) on core-shell magnetic nanoparticles and self-polymerization of dopamine (DA).
引用
收藏
页码：3541 / 3544
页数：4
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