Copper-catalyzed synthesis of esters from ketones. Alkyl group as a leaving group

被引：12

作者：

Nakatani, Yuji ^{[1
]}

Koizumi, Yuichiro ^{[1
]}

Yamasaki, Ryu ^{[1
]}

Saito, Shinichi ^{[1
]}

机构：

[1] Tokyo Univ Sci, Fac Sci, Dept Chem, Tokyo 1628601, Japan

来源：

ORGANIC LETTERS | 2008年 / 10卷 / 10期

关键词：

D O I：

10.1021/ol800576w

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The conversion of ketones to esters has been achieved through the use of Cu catalyst and tetrabutylammonium nitrite. This reaction involves the activation of the less activated C-C bond, and the alkyl group is removed as a leaving group. Various isopropyl ketones are found to be good substrates for this reaction.

引用

页码：2067 / 2070

页数：4

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