Copper-catalyzed synthesis of esters from ketones. Alkyl group as a leaving group

被引：12
|
作者：
Nakatani, Yuji [1 ]
Koizumi, Yuichiro [1 ]
Yamasaki, Ryu [1 ]
Saito, Shinichi [1 ]
机构：
[1] Tokyo Univ Sci, Fac Sci, Dept Chem, Tokyo 1628601, Japan
来源：
ORGANIC LETTERS | 2008年 / 10卷 / 10期
关键词：
D O I：
10.1021/ol800576w
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
The conversion of ketones to esters has been achieved through the use of Cu catalyst and tetrabutylammonium nitrite. This reaction involves the activation of the less activated C-C bond, and the alkyl group is removed as a leaving group. Various isopropyl ketones are found to be good substrates for this reaction.
引用
收藏
页码：2067 / 2070
页数：4
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