Highly efficient single and multi-gene knockout with CRISPR/Cpf1 in T cells for the development of improved cell therapies

被引：0
|
作者：
Zuris, J. A. [1 ]
Viswanathan, R. [1 ]
Loveluck, K. [1 ]
Fang, J. W. [1 ]
Chin, M. S. [1 ]
DaSilva, J. A. [1 ]
Wang, T. [1 ]
Gotta, G. M. [1 ]
Harbinski, F. [1 ]
Marco, E. [1 ]
Wilson, C. J. [1 ]
Welstead, G. G. [1 ]
Myer, V. E. [1 ]
Fernandez, C. A. [1 ]
机构：
[1] Editas Med, Cambridge, MA USA
来源：
HUMAN GENE THERAPY | 2018年 / 29卷 / 12期
关键词：
D O I：
暂无
中图分类号：
Q81 [生物工程学（生物技术）]; Q93 [微生物学];
学科分类号：
071005 ; 0836 ; 090102 ; 100705 ;
摘要：
P257
引用
收藏
页码：A103 / A103
页数：1
相关论文
共 50 条
  • [1] Strategies for Multi-Gene Editing and Reduction of Translocations with CRISPR-CPF1 in T Cells for the Development of Improved Cell Therapies
    Zuris, John A.
    Bothmer, Anne
    Viswanathan, Ramya
    Abdulkerim, Hayat S.
    Gareau, Ken
    Winston, Stephen M.
    Scott, Sean N.
    Fang, Justin W.
    Chin, Melissa S.
    DaSilva, Jennifer A.
    Wang, Tongyao
    Gotta, Gregory M.
    Borges, Christopher M.
    Harbinski, Fred
    Marco, Eugenio
    Wilson, Christopher J.
    Welstead, G. Grant
    Myer, Vic E.
    Fernandez, Cecilia A.
    MOLECULAR THERAPY, 2019, 27 (04) : 105 - 106
  • [2] Generation of Transgenic Rat Embryonic Stem Cells Using the CRISPR/Cpf1 System for Inducible Gene Knockout
    Vladimir V. Sherstyuk
    Suren M. Zakian
    Biochemistry (Moscow), 2021, 86 : 843 - 851
  • [3] Generation of Transgenic Rat Embryonic Stem Cells Using the CRISPR/Cpf1 System for Inducible Gene Knockout
    Sherstyuk, Vladimir V.
    Zakian, Suren M.
    BIOCHEMISTRY-MOSCOW, 2021, 86 (07) : 843 - 851
  • [4] Multi-gene precision editing tool using CRISPR-Cas12a/Cpf1 system in Ogataea polymorpha
    Hou, Senqin
    Yang, Shibin
    Bai, Wenqin
    MICROBIAL CELL FACTORIES, 2025, 24 (01)
  • [5] Multiplex gene editing by CRISPR–Cpf1 using a single crRNA array
    Bernd Zetsche
    Matthias Heidenreich
    Prarthana Mohanraju
    Iana Fedorova
    Jeroen Kneppers
    Ellen M DeGennaro
    Nerges Winblad
    Sourav R Choudhury
    Omar O Abudayyeh
    Jonathan S Gootenberg
    Wen Y Wu
    David A Scott
    Konstantin Severinov
    John van der Oost
    Feng Zhang
    Nature Biotechnology, 2017, 35 : 31 - 34
  • [6] Development of a CRISPR/Cpf1 system for multiplex gene editing in Aspergillus oryzae
    Chen, Tianming
    Chen, Ziming
    Zhang, Huanxin
    Li, Yuzhen
    Yao, Lihua
    Zeng, Bin
    Zhang, Zhe
    FOLIA MICROBIOLOGICA, 2024, 69 (02) : 373 - 382
  • [7] Development of a CRISPR/Cpf1 system for multiplex gene editing in Aspergillus oryzae
    Tianming Chen
    Ziming Chen
    Huanxin Zhang
    Yuzhen Li
    Lihua Yao
    Bin Zeng
    Zhe Zhang
    Folia Microbiologica, 2024, 69 : 373 - 382
  • [8] Erratum: Multiplex gene editing by CRISPR–Cpf1 using a single crRNA array
    Bernd Zetsche
    Matthias Heidenreich
    Prarthana Mohanraju
    Iana Fedorova
    Jeroen Kneppers
    Ellen M DeGennaro
    Nerges Winblad
    Sourav R Choudhury
    Omar O Abudayyeh
    Jonathan S Gootenberg
    Wen Y Wu
    David A Scott
    Konstantin Severinov
    John van der Oost
    Feng Zhang
    Nature Biotechnology, 2017, 35 : 178 - 178
  • [9] Development of a CRISPR/Cpf1 system for targeted gene disruption in Aspergillus aculeatus TBRC 277
    Dede Abdulrachman
    Lily Eurwilaichitr
    Verawat Champreda
    Duriya Chantasingh
    Kusol Pootanakit
    BMC Biotechnology, 21
  • [10] Development of a CRISPR/Cpf1 system for targeted gene disruption in Aspergillus aculeatus TBRC 277
    Abdulrachman, Dede
    Eurwilaichitr, Lily
    Champreda, Verawat
    Chantasingh, Duriya
    Pootanakit, Kusol
    BMC BIOTECHNOLOGY, 2021, 21 (01)
12345