Strategies for Multi-Gene Editing and Reduction of Translocations with CRISPR-CPF1 in T Cells for the Development of Improved Cell Therapies

被引：0

作者：

Zuris, John A. ^{[1
]}

Bothmer, Anne ^{[1
]}

Viswanathan, Ramya ^{[1
]}

Abdulkerim, Hayat S. ^{[1
]}

Gareau, Ken ^{[1
]}

Winston, Stephen M. ^{[1
]}

Scott, Sean N. ^{[1
]}

Fang, Justin W. ^{[1
]}

Chin, Melissa S. ^{[1
]}

DaSilva, Jennifer A. ^{[1
]}

Wang, Tongyao ^{[1
]}

Gotta, Gregory M. ^{[1
]}

Borges, Christopher M. ^{[1
]}

Harbinski, Fred ^{[1
]}

Marco, Eugenio ^{[1
]}

Wilson, Christopher J. ^{[1
]}

Welstead, G. Grant ^{[1
]}

Myer, Vic E. ^{[1
]}

Fernandez, Cecilia A. ^{[1
]}

机构：

[1] Editas Med, Cambridge, MA USA

来源：

MOLECULAR THERAPY | 2019年 / 27卷 / 04期

关键词：

D O I：

暂无

中图分类号：

Q81 [生物工程学（生物技术）]; Q93 [微生物学];

学科分类号：

071005 ; 0836 ; 090102 ; 100705 ;

摘要：

208

引用

页码：105 / 106

页数：2

共 49 条

[1] Highly efficient single and multi-gene knockout with CRISPR/Cpf1 in T cells for the development of improved cell therapies
Zuris, J. A.
Viswanathan, R.
Loveluck, K.
Fang, J. W.
Chin, M. S.
DaSilva, J. A.
Wang, T.
Gotta, G. M.
Harbinski, F.
Marco, E.
Wilson, C. J.
Welstead, G. G.
Myer, V. E.
Fernandez, C. A.
HUMAN GENE THERAPY, 2018, 29 (12) : A103 - A103
[2] Multiplex Gene Editing in Rice Using the CRISPR-Cpf1 System
Wang, Mugui
Mao, Yanfei
Lu, Yuming
Tao, Xiaoping
Zhu, Jian-kang
MOLECULAR PLANT, 2017, 10 (07) : 1011 - 1013
[3] In Vitro Gene Editing Catalyzed by CRISPR-Cpf1 and a Mammalian Cell-Free Extract
Sansbury, Brett
Wagner, Amanda
Kmiec, Eric
MOLECULAR THERAPY, 2018, 26 (05) : 232 - 232
[4] Multiplex gene editing by CRISPR-Cpf1 using a single crRNA array
Zetsche, Bernd
Heidenreich, Matthias
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Fedorova, Iana
Kneppers, Jeroen
DeGennaro, Ellen M.
Winblad, Nerges
Choudhury, Sourav R.
Abudayyeh, Omar O.
Gootenberg, Jonathan S.
Wu, Wen Y.
Scott, David A.
Severinov, Konstantin
van der Oost, John
Zhang, Feng
NATURE BIOTECHNOLOGY, 2017, 35 (01) : 31 - 34
[5] A split CRISPR-Cpf1 platform for inducible genome editing and gene activation
Nihongaki, Yuta
Otabe, Takahiro
Ueda, Yoshibumi
Sato, Moritoshi
NATURE CHEMICAL BIOLOGY, 2019, 15 (09) : 882 - +
[6] Multiplex gene editing in rice with simplified CRISPR-Cpf1 and CRISPR-Cas9 systems
Mugui Wang
Yanfei Mao
Yuming Lu
Zhidan Wang
Xiaoping Tao
Jian-Kang Zhu
Journal of Integrative Plant Biology, 2018, 60 (08) : 626 - 631
[7] Establishment of the CRISPR-Cpf1 gene editing system in Bacillus licheniformis and multiplexed gene knockout
Liu, Suxin
Xiao, Fengxu
Li, Youran
Zhang, Yupeng
Wang, Yanling
Shi, Guiyang
SYNTHETIC AND SYSTEMS BIOTECHNOLOGY, 2025, 10 (01) : 39 - 48
[8] Multiplex gene editing in rice with simplified CRISPR-Cpf1 and CRISPR-Cas9 systems
Wang, Mugui
Mao, Yanfei
Lu, Yuming
Wang, Zhidan
Tao, Xiaoping
Zhu, Jian-Kang
JOURNAL OF INTEGRATIVE PLANT BIOLOGY, 2018, 60 (08) : 626 - 631
[9] Detection and Modulation of DNA Translocations During Multi-Gene Genome Editing in T Cells
Bothmer, Anne
Gareau, Kenneth W.
Abdulkerim, Hayat S.
Buquicchio, Frank
Cohen, Lucas
Viswanathan, Ramya
Zuris, John A.
Marco, Eugenio
Fernandez, Cecilia A.
Myer, Vic E.
Cotta-Ramusino, Cecilia
CRISPR JOURNAL, 2020, 3 (03): : 177 - 187
[10] CRISPR-Cpf1 Editing and Hairy Root Evaluation of Gene Targets to Obtain Low Phytate Soybean
Carrijo, Jessica
LaFayette, Peter
Vianna, Giovanni R.
Aragao, Francisco
Parrott, Wayne
IN VITRO CELLULAR & DEVELOPMENTAL BIOLOGY-ANIMAL, 2019, 55 : S60 - S61

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